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doi: 10.1186/s12974-021-02237-5 274 WangXLiMDiaoKWangYChenHZhaoZet al

Speeding up and slowing down enzyme function: Several important variants in the CYP2D6 gene can cause the enzyme to function differently either by speeding up or slowing down the rate by which the medications break down

Mouse major urinary proteins, primarily expressed in the liver, and circulating major urinary proteins regulate metabolism by suppressing hepatic gluconeogenesis and lipid metabolism (Charkoftaki et al., 2019)