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The nephroprotection exerted by curcumin in maleate-induced renal damage is associated with decreased mitochondrial fission and autophagy

The egg number, weight, and mass decreased significantly, while cracked eggs increased dramatically in AFT-intoxicated birds versus all other treated groups

Vancamelbeke, M

The increased oxidative stress seems to be the second hit in the progression from NAFL to NASH: the increase in ROS and consequently in lipid peroxidation has been associated to hepatocellular damage, inflammation, and eventual fibrosis due to the activation of hepatic stellate cells