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Brighten: Welcome back to the Dr

Designed for clinicians and health professionals, this program offers a systems-based framework for understanding cardiovascular risk through the lens of redox biology and mitochondrial health, with practical implications for prevention and personalized care

12, 13 The oncogenic transcription factor MYC mediates the transcription of almost all the genes involved in glycolysis and glutaminolysis, 6, 14 and it promotes shuttling of glycolytic intermediates to pentose phosphate pathway to generate large quantities of reduced nicotinamide adenine dinucleotide phosphate (NADPH) and promote macromolecule biosynthesis via the induction of pyruvate kinase isozymes M2 (PKM2)