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Acknowledgments The authors acknowledge the funding of the National Natural Science Foundation of China [No.82173989] and the support from the National Administration of Traditional Chinese Medicine [No.zyyzdxk-2023272]

Both the LEAN and SEMA-NASH trials showed that GLP-1RA slowed fibrosis progression and improved non-invasive markers of fibrosis but failed to demonstrate significant histological modifications 93

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Further studies are requisite to confirm their efficacy and safety

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