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A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death

doi:10.1101/cshperspect.a009183 Acknowledgments This work was supported by the Chang Gung Memorial Hospital [Grants CMRPD1A0531, CMRPD1C0231, CMRPG391311, CMRPG3A1131] and the Ministry of Science and Technology, Taiwan [Grant NMRPD181001-3]

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reported as mean +/ SD

Gastroenterology 149 , 379388 (2015)

Future research should elucidate the precise mechanisms of celastrol in diverse kidney diseases to establish a robust theoretical foundation for precision medication