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Concurrent attention should be given to psychological support and social factors, alongside recommending scientifically grounded lifestyle modifications ( Figure 2 )

Nicolini Y, Tramacere A, Parmigiani S, Dadomo H

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In addition, the INH concentrations (36 mM) used in our study define the mechanistic threshold for INH-induced OS, modeling elevated systemic ROS exposure in vulnerable patients such as those with G6PD deficiency or slow acetylator status who exhibit impaired drug metabolism, which is a standard approach for toxicological studies ( The integrated HepG2 transcriptomics and experimental erythrocyte validation robustly links molecular changes to INH-induced cellular dysfunction