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The studys primary purpose was to see the neurodevelopmental abnormalities that might be caused by prenatal valproic acid exposure and whether resveratrol could be utilized as a treatment [96]

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Furthermore, brain organoids and three-dimensional culture models are employed for high-throughput drug screening because they can replicate the networks involved in iron metabolism in the human brain ( 3.5 Stroke 3.5.1 Ischemic stroke Mounting studies have revealed that ischemic stroke increases iron deposition, mitochondrial dysfunction, LP, and iron overload

Accordingly, apolipoproteins (apoB and apoE) and apolipoprotein peptides have been used as LDL-receptor-mediated brain targeting ligands [26]