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Thus, more than genes of major effect, evidence suggest that there are multiple susceptibility loci, each one with small effect

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Adrenal overactivation in response to chronic gut inflammation produces a flattened diurnal cortisol curve with characteristic early afternoon collapse

Moreover, studies linking the severity of bipolar symptoms to tardive dyskinesia, even in the absence of pharmacotherapy, lend further support to claims of dopamine dysfunction in this disease state (246)

However, the exact mechanisms underlying the effects of GSH on HF are elusive