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Moreover, increases in the levels of proinflammatory cytokines, catecholamines, cortisol, glucagon, and acute phase proteins as a result of stroke lead to alterations in metabolic balance in favor of protein catabolism and muscle and body mass wasting [7, 9]

A randomized, double-blind, placebo-controlled trial in 28 older women (ages, 65-70 years) found no effect of L-carnitine supplementation (1.5 g/day for 24 weeks) on serum pro-inflammatory cytokine concentrations, body mass and composition (lean [fat-free] mass and skeletal muscle mass), or measures of skeletal muscle strength (123)

JAMA 321 , 175187 (2019)

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[DOI] [Google Scholar] 148.Dwyer J.T., Bailen R.A., Saldanha L.G., Gahche J.J., Costello R.B., Betz J.M., Davis C.D., Bailey R.L., Potischman N., Ershow A.G