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DOI: Published: Publisher Name: Springer, Singapore Print ISBN: 978-981-10-7166-9 Online ISBN: 978-981-10-7167-6 eBook Packages: MedicineMedicine (R0)

Smoking and excessive alcohol intake contribute to stress, reducing enzyme efficiency, whereas moderation preserves balance

As an antioxidant, NAC acts as a reduced thiol donor that supports glutathione resynthesis and may exhibit other antioxidant properties (102, 211)

Activation of Nrf2 by either cellular redox status or pharmacological intervention leads to the up-regulation of over 250 genes encoding proteins that are involved in antioxidant defense systems, redox homeostasis, and xenobiotic detoxification [81]

Increased specific interfacial areas, more controllable interfacial interactions, higher overall compliance, and achievable loads are among the advantages of nanofiller technology over conventional fillers like carbon fibers, glass fibers, metal particles, wood sheets, and inorganic mineral particles [38]

In contrast to pyruvate carboxylase deficiency, fasting hypoglycemia and hyperammonemia are not expected features of pyruvate dehydrogenase complex deficiency