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[40] demonstrated in vitro that a decrease in endogenous N/OFQ, or the absence of its receptor, results in an increase in capsaicin-induced bronchoconstriction, indicating the ability of this neuropeptide to modulate bronchoconstriction by affecting sensory fibers

It occurs naturally in human plasma, though levels decline significantly with age

doi: 10.1093/jxb/erp097 3 AlricJ.JohnsonX

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The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene

doi: 10.3389/fphar.2023.1267765 Received 27 July 2023 Accepted 09 October 2023 Published 13 November 2023 Volume 14 - 2023 Edited by Xinwang Yang, Kunming Medical University, China Reviewed by Yipeng Wang, Soochow University, China Lin Wei, Anhui Medical University, China Updates Copyright 2023 He, Wang and Qu