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Lysine demethylase KDM2A inhibits TET2 to promote DNA methylation and silencing of tumor suppressor genes in breast cancer

106,107 Behaviors associated with stress and anxiety include: destructive behavior, fear aggression, inappropriate urination/defecation, vocalization, vomiting, salivation, panting, increased heart rate and stress hormone production, hiding, pacing, cowering/lowered body posture, shaking/trembling, escape attempts/retreating, and seeking out familiar people

Several genes associated with glaucoma pathology encode various players in the mitophagy pathway, such as fusion proteins mitofusin-2 (MFN-2) and optic atrophy-1 (OPA-1), which regulate mitochondrial fusion (Hu et al., 2018)

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Potassium adduct of 2 was also observed at m/z = 391 [ 2 + K2 H] (Fig