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This experimental series pleads for extending research to the human level

H., Sampaio, F

Statistical analysis involved counting changes in fissures and average neuron density observed in individual brain sections analyzed per microscopy field

Clinical outcomes The beneficial effects of riboflavin on biochemical (Reference Al-Harbi, Imam and Nadeem22,Reference Alhazza, Hassan and Ebaid23,Reference Bashandy, Ebaid and Moussa26,Reference Alam, Iqbal and Naseem31) and histopathological findings (Reference Al-Harbi, Imam and Nadeem22,Reference Alhazza, Hassan and Ebaid23,Reference Al-Harbi, Imam and Nadeem25Reference Karakoyun, Erta and Yksel27,Reference Sakarcan, Erahin and Eminolu30Reference Yu, Morimoto and Yu32) and clinical symptoms (Reference Sakarcan, Erahin and Eminolu30,Reference Yu, Morimoto and Yu32) , reported concurrent with alleviated oxidative stress in animals, suggest that riboflavin antioxidant activity may lead to promising clinical outcomes in these conditions

Taking more than the advanced dose rarely leads to faster or better results and significantly increases the risk of side effects (e.g., water retention, numbness, nausea)

Long-term oral use was well tolerated by rats, pigs, and monkeys