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However, performing negative screenings for each of substrate and intermediates in hydroxytyrosol biosynthetic pathway is time-consuming

220 , following the successful example of asparagine limitation by asparaginase for the treatment of acute lymphoblastic leukemia 221

As emphasized by Professor Carmel, neurological recovery starts within the initial week of initiating treatment, and it generally reaches completion in 1.5 to 3 months

For example, sortilin has been demonstrated to sort proBDNF to the regulated secretory pathway in neurons [9]

Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as Doorstop for NADPH Entry

10 ng RNA was used for the SMART-Seq v4 Ultra Low Input RNA Kit for sequencing with the Nextera XT DNA Library Preparation Kit