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doi: 10.3109/15513815.2012.659410 27 PontesFSCde SouzaLLde AbreuMCFernandesLARodriguesALMdo NascimentoDMet al

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609 PARP inhibitor Actovegin: Actovegin ameliorated sensory nerve conduction velocity (SNCV) and IENFD of experimental DN via mechanisms involving suppression of PARP activation

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We show that UNC1 functions noncell autonomously, in neurons, and disruption of the gene led to secretion of an excess of a sulphated signal that activates NHR1 in different tissues