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June 25, 2025

This leads to metabolic effects that are still not fully understood, which ultimately result in body weight reduction [204]

N Engl J Med 312(3):137141

Therefore, it would seem more appropriate to set up a VLCKD protocol with the use of meal replacements to determine greater safety, efficacy, and compliance in patients with obesity, with preference given to freeze-dried meal replacements, which generally have a higher protein content and lower fat and carbohydrate content

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