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Underlying mechanisms of apoptosis in HepG2 cells induced by polyphyllin I through fas death and mitochondrial pathways

doi:10.22074/cellj.2016.4872 [35] Malik R, Hodgson H

60 TyurinaY

Terasawa et al

Two aromatic residues, Phe152 and Tyr270, might also play a role in preventing hydrolysis of the intermediate since both residues form hydrophobic walls about the GSHbinding pocket