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10.1126/science.1086071 34 ClevelandD

PLOS ONE 8 , e61053 (2013)

RP is characterized by the loss of rod and cone photoreceptors in the retina due to many compounding factors, including oxidative damage

Formation of glutathione-S-conjugates with 4-DMAP has been shown to occur in vitro in red cells (Eyer & Kiese, 1976), and in vivo in dogs (Eyer & Gaber, 1978) and man (Jansco et al., 198l, Klimmek et al., 1983)