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Another abnormality present in patients with ME/CFS is the presence of fibrinolysis-resistant amyloid fibrin microbleeds and platelet hyperactivation [78], which could also be a consequence of the overproduction of proinflammatory cytokines or due to the binding of EBERs to TLR3 [231,232,233, 308, 309]

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References Castellano I, Merlino A

Ganoderma lucidum polysaccharides significantly increase acetate, propionate, and butyrate levels (140, 141)

Each model used to study cell replacement therapies will provide insights into controlling the retinal microenvironment in optic neuropathies to support successful donor RGC grafting