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After being consumed by endogenous cells and reversing their pathogenic changes, natural or synthetic EXOs interacting with them may offer therapeutic benefits (Si et al., 2023)

Kidney stone formation is associated with a significantly increased risk of cardiovascular disease, likely related to underlying mechanisms, including vascular calcification, oxidative stress, endothelial dysfunction, and cholesterol-induced pathology (Muschialli 2024)

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Although gut bacteria have been extensively studied, intestinal fungi remain relatively under-explored, despite accounting for about 0.1% of the gut microbiota 7

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