bacterial and host-derived glutathione are required to activate prfa Control of Virulence through the Peptide Signature of the Habitat PrfA, the master virulence regulator
PrfA, the master virulence regulator of Listeria monocytogenes: structuralfunctional insights, regulatory architecture, and antivirulence strategies Molecular Biology Reports Springer Nature Link Modulation of bacterial virulence and fitness by host glutathione ScienceDirect C di AMP accumulation disrupts glutathione metabolism in Listeria monocytogenes Infection and Immunity Allosteric GSH binding primes PrfA for DNA binding. (A and B) Download Scientific Diagram 5LRR: The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione RCSB PDB Streptococcus pyogenes Hijacks Host Glutathione for Growth and Innate Immune Evasion mBio
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