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10.1542/peds.113.5.e472

Indian J Dermatol 56(4):407411

Russian clinical trials have contributed valuable data, but methodological differences, including smaller sample sizes, different statistical approaches, and less rigorous blinding procedures compared to FDA standards, mean that Western regulatory agencies generally do not accept this data for drug approval

However, even with the very fast and improved methodology, we seemed to have reached the limit for DDA for phosphoproteomics with current instrumentation