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This was the torcetrapib drug, which was designed specifically to block the transfer of cholesterol from HDL particles to LDL particles, and thus was very effective at reducing the total-to-HDL cholesterol ratio

10.1007/s00125-015-3634-4 Summary Keywords hepatocyte growth factor, HGF, obesity, insulin resistance, diabetes, inflammation, beta cells Citation Oliveira AG, Arajo TG, Carvalho BM, Rocha GZ, Santos A and Saad MJA (2018) The Role of Hepatocyte Growth Factor (HGF) in Insulin Resistance and Diabetes

Herpes simplex virus type 1 classically causes a severe, necrotizing encephalitis localizing to the temporal lobes, presenting with altered mental status and seizures

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The bound protein was eluted using binding buffer supplemented with 150 mM imidazole at a flow rate of 3 ml/min and applied onto the HiTrap SP FF 5-ml column (pre-equilibrated with 20 mM sodium phosphate, pH 6.0, with 50 mM NaCl) at a flow rate of 1 ml/min