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These findings emphasize the metabolic heterogeneity of GBM and highlight glycolysis not just as an energy strategy, but as a fundamental driver of tumor proliferation and biosynthesis

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Sensitivity The analytical sensitivity of the assay is 34.34 U

A smaller subset of cases (approximately 4%) involves one allele with a GAA repeat expansion and the other allele carrying a different mutation, such as a deletion or point mutation (Bidichandani, 1998)

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