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Specifically, the piRNA piR-hsa-30937, found in small extracellular vesicles from pancreatic neuroendocrine neoplasms, can be released into the microenvironment and enhance CD276 expression in macrophages via the PTEN/AKT pathway, leading CD276 + TAMs to inhibit T-cell antitumor immunity 663 (Fig

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The timeframes of infection relapse due to the same or a novel strain did not differ (within 108 days), although the sample size was limited ( n = 21)

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