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Different from canonical autophagy, STING-elicited noncanonical autophagy operates independently of upstream autophagy modulators, including unc-51-like kinase 1 (ULK1), Beclin-1, and ATG9a, yet relies on downstream autophagy regulators such as ATG5 and ATG16L1 ( 6.3 Viruses evade host immune defence by inducing autophagic degradation of cGAS/STING Viruses have also evolved unique mechanisms to ensure their survival by influencing autophagy processes and cGAS-STING signalling

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Nutrients 12, 282

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