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However, during apoptosis, the mitochondrial membrane potential is lost and the mitochondrial permeability transition pore (MPTP) remains open, allowing TMRE to escape into the cytoplasm, resulting in a significant reduction of orange-red fluorescence within the mitochondria [44]

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CNS diseases, including spinal cord injury (SCI), traumatic brain injury (TBI), ischemic stroke (IS), and hemorrhagic stroke (e.g., subarachnoid hemorrhage [SAH] and intracerebral hemorrhage [ICH]), result in extensive neuronal death

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209, 721 (2015), Abstract Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy: C.K

Express 11 (1), 104