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444 Many studies suggest that high glucose triggers increased mitochondrial fission in retinal capillaries, which induces cell death through the activation of pro-apoptotic genes and other methods, thereby triggering diabetic retinopathy

doi: 10.1016/j.cbi.2025.111494 206 ChenCZhangWZhouTLiuQHanCHuangZet al

Dosage Gary Brecka uses 10X Optimize, a methylated multivitamin, and prefers two tablets per day (source)

Theranostics (2025) 15(6):262448

Several plant foods are also good sources

Mills EA, Ogrodnik MA, Plave A, Mao-Draayer Y (2018) Emerging understanding of the mechanism of action for dimethyl fumarate in the treatment of multiple sclerosis