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de Potter, B

Pulmonary fibrosis and oxidative stress model: NF-B / Nrf2 signaling pathway involvement: Redox Biology publication examining oxidative regulation mechanisms: These studies describe GHK-Cu interacting with redox-sensitive signaling networks and inflammatory mediators

Chaban, O

Research conducted by Hui-Hui Xiao and colleagues (156) demonstrated that OVX rats exhibited dyslipidemia, abnormal bile acid metabolism, and insulin resistance, which were correlated with an elevated Firmicutes / Bacteroidetes (F/B) ratio a well-recognized biomarker for steroid deficiency-induced metabolic and skeletal disorders

Picciotto et al., 2015) as well as elevation of cortisol (Walker et al., 1990), which in turn is associated with IOP elevation (Schwartz and Seddon, 1981) and vascular dysregulation with relevance to Flammer syndrome or endothelial dysfunction-mediated glaucoma (Buckley et al., 2002

This, in turn, promotes NCOA4-mediated ferritinophagy, resulting in elevated intracellular iron levels and lipid peroxidation, ultimately triggering ferroptosis and contributing to osteoporotic pathology