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Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells

B Vitamins B vitamins are important for nervous system function and have been tested for prevention of CIPN

J Pharm Sci 1995;84(5):627-633

10.1016/j.yexcr.2017.04.016 90 JasialS.GilbergE.BlaschkeT.BajorathJ

A trade-off threshold between number of input features and predictive power was assessed manually for each model

The low initial dose is recommended, and increase incrementally, titrating to effect ( Cyproheptadine is a first-generation antihistamine used in GI disorders for its serotonin (5HT2) and calcium channel antagonist effects (143, 144)