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Moreover, as the mechanistic link is primarily inferred through pharmacological blockade, additional studies using direct molecular markers like p-Akt/t-Akt are needed to substantiate the role of FGF1/PI3K/Akt signaling in Tozasertibs action

These interactions can significantly enhance drug penetration, therefore prolonging the drugs retention time in the posterior segment of the eye [32]

Harischandra DS, Jin H, Anantharam V et al (2015) -Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinsons disease

In Teichman et al

Another important aspect of astrocytic metabolism, namely glutamine uptake and conversion, was studied in the context of frontotemporal dementia