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doi: 10.1016/j.cell.2010.10.002

Hypertension, often called the silent killer, can cause serious damage to the heart, brain, and kidneys without noticeable symptoms

2.6 Dosage Modifications for Adverse Reactions Obtain complete blood count on Days 1, 8, and 15 of each cycle

Intermittent 10-20 day cycles are standard

This can lead to focusing on one condition while missing others, or to attributing all difficulties to a single diagnosis when multiple conditions may be present