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Besides, significantly greater CSF levels of transforming growth factor 1 (TGF-1), IL-1, and IL-6 were also observed in PD patients than those in controls, according to a systematic study of CSF cytokines in PD patients (Chen et al., 2018)

The combined treatment regime showed a histopathology almost similar to the sham control group, indicating a near-complete reversal of the injurious effects of sepsis

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