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Genes Dev 31(4):370-382, 2017

Dendritic cell-based immunotherapies show therapeutic potential by enhancing antitumour T cell responses 100,104

& Brodsky, R

doi: 10.1038/sj.onc.1206940 29 SorollaMAHidalgoISorollaAMontalRPallisOSaludAet al

Instead, oxygen has to diffuse from the closest blood vessels into the rest of the tumor, making it very difficult for oxygen to reach every single cell in the inner parts of the tumor ( Figure 1 )