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The calibrated model was able to capture the dynamics observed in the experimental data (Fig

o Monoclonal antibody-based (clone KKU505) reactive to excretory-secretory antigens of O

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The identification of reliable validated biomarkers could facilitate earlier and more accurate diagnosis and drive the development of targeted pharmacological therapies that might address the underlying pathophysiology of these diseases

High lipophilicity (Log P 3) increases a drugs permeability and uptake, enhancing biotransformation and potentially leading to higher levels of toxic metabolites

Clinically, curcumin should be considered an adjunct within supportive-care pathways rather than a standalone therapy