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Initial improvements in skin texture and radiance often become apparent within 4-6 weeks of consistent use

Definitions of antidepressant treatment response, remission, nonresponse, partial response, and other relevant outcomes: a focus on treatment-resistant depression

In clinical trials at the 12 mg dose, researchers documented nausea in 28% of participants, diarrhea in 23%, constipation in 17%, and vomiting in 12%

Pharmacologic agents, especially modern potassium binders, allow more dietary flexibility , enabling patients to benefit from plant-based diets without increased hyperkalemia risk

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10.1016/S0006-291X(02)00602-2 60 LiD.LiuX.PiW.ZhangY.YuL.XuC.et al (2022)