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Mol Endocrinol (2011) 25(12):2094105

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Riedel, M

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Transforming the concept of connectivity: unveiling tunneling nanotube biology and their roles in brain development and neurodegeneration

However, administration of GH and subsequent GH-mediated effects were found to be dose dependent, as high concentrations given to GH-deprived canines caused atrophy of testes and accessory organs, thinning of prostatic epithelium and a reduction in LH and testosterone levels (75)