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Six randomized, double-blind, placebo-controlled trials involving over 900 participants demonstrated that this growth hormone fragment peptide is well-tolerated with a safety profile indistinguishable from placebo

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Similarly, to compare the relative effects of multiple NNMT inhibitors on NNMT activity in cultured adipocytes, differentiated adipocytes in 6-well plates were treated with 10 M test compound for 24 h