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Description

CrossRef A synergic GLP-1/Acylethanolamide-based combined therapy for MAFLD: Studies in rat models Marialuisa de Ceglia, Rubn Tovar, Miguel Rodrguez-Pozo, Antonio Vargas, Ana Gavito, Juan Surez, Elena Baixeras, Fernando Rodrguez de Fonseca, Juan Decara Biochemical Pharmacology.2025

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The cellular Nrf2 level is quite low in normal unstressed situations, but it substantially increases when exposed to electrophilic compounds or reactive oxygen species (ROS) (Zhang and Hannink, 2003)

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However, their prolonged use has been linked to serious complications, including osteoporosis, hypertension, diabetes, and increased susceptibility to infections [29]

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doi: 10.1038/s41598-017-15668-z 61 YeePPWeiYKimSYLuTChihSYLawsonCet al

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