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All patients received supplementation with folic acid (500 g p.o., daily) and vitamin B 12 (1000 g i.m., every 9 weeks) commencing 1 week before the first cycle and continuing until the discontinuation of chemotherapy

Adults over 50 who often have reduced stomach acid and therefore absorb less B12

Widely studied in preclinical laboratory models, BPC-157 has generated significant scientific interest for its potential role in cellular signaling, tissue remodeling research, angiogenesis pathways, and gastrointestinal integrity studies

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Some people benefit from starting with IV therapy to quickly address deficiencies, then transitioning to regular B12 shots for maintenance

Long-term use of acid-reducing drugs can result in deficiencies, making supplementation in this area important