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& Kashtan, C

Hippocampal neurons were maintained in Neurobasal A media from Invitrogen (Carlsbad, CA) supplemented with B27 from Invitrogen, 0.5 mM L- glutamme, and 5mM cytosine-D-arabinofuranoside from Sigma added at 2 days in vitro

The mRNA ORFs for the A2- D185P and A2-T160F_N46V constructs are set forth in SEQ ID NO: 6 and SEQ ID NO: 8, respectively

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and the red cross denotes receptor antagonism

For researchers running their first cagrilintide protocol, the 5mg vial offers the best balance between cost efficiency and practical dosing flexibility