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H 2 O 2 level is proportional to the luminescent signal which was measured by a multi-mode microplate reader (FLUOstar Omega)

B12 interactions with other medications are also a consideration

Eligibility to participate was assessed based on medical history, physical examination, routine clinical laboratory tests, urine pregnancy tests for females, and inclusion/exclusion criteria (Table S1)

Vitamin B12 deficiency is relatively rare, but it can occur in people with certain medical conditions, such as pernicious anemia, making it difficult to absorb the vitamin from food or supplements

But, sometimes the body has trouble processing these nutrients through natural digestive functions alone

This review consolidates recent findings indicating that FOXO4-dependent senescence significantly contributes to neuroinflammation, synaptic dysfunction, and impaired neurogenesis in the aging brain