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Mast cells play a protective role by degrading and neutralizing A

In doxorubicin-resistant human uterine sarcoma (MES-SA/Dx5), apigenin reduces intracellular glutathione (GSH) levels by inhibiting ATP-binding cassette subfamily B member 1 (ABCB1) [60], while in prostate cancer, it reverses doxorubicin resistance by down-regulating ABCB1 protein expression [61]

No clinical or laboratory signs of toxicity or intolerance were observed, indicating a favorable safety profile

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The vast majority of the active antioxidant is destroyed before it ever reaches your bloodstream

Reduced plasma nonesterified fatty acid levels and the advent of an acute lung injury in mice after intravenous or enteral oleic acid administration