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For Atlantic salmon it is of particular interest because there have been significant variations in the vitamin B12 content in salmon the last 15 years (Moxness Reksten et al., 2022), which influences the commercial value of the fish, as well as growth and other physiological parameters

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Giraldo JP, Markita PL, Sean MF, Thomas PMN, Nicole MI, Ardemis AB, et al

Compounds such as alantolactone, which target glycolytic enzymes, including LDHA, PFKL, and HK2, have also been shown to increase cisplatin sensitivity in ovarian cancer [63]

Oftentimes, too-high levels of oxidative stress and Glutathione depletion can lead to multiple diseases, including neurodegenerative disorders (Alzheimers, Parkinsons), pulmonary disease (asthma, COPD), immune disease (HIV, autoimmune disease), cardiovascular diseases (hypertensions), liver disease, cystic fibrosis, and aging

This novel pathway may represent a new therapeutic target for preventing ALD and perhaps non-alcoholic liver steatosis