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This consideration affects protocol design and subject selection in research settings

Consequently, it is also postulated that Sermorelin may retain the fundamental capability of GHRH, potentially stimulating the intermittent release of growth hormone by engaging GHRH receptors in the pituitary gland

1998 Modified GRF(1-29) used in GHRH-deficient and age-related GH decline animal models to study GHRH receptor replacement activity and GH secretory capacity restoration