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The initiation of lipid peroxidation necessitates the abstraction of diallyl hydrogen atoms positioned between the two carbon-carbon double bonds from polyunsaturated PUFA-PL on phospholipids, resulting in the formation of carbon-centered free radicals (PL-) that subsequently react with molecular oxygen to generate lipid peroxy radicals (PLOO-)

As the body ages, or suffering from other diseases such as stroke, HIV, cancer, etc., glutathion level starts decreasing

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Women using oral contraceptives should be counseled about this potential interaction and may need to consider alternative or additional contraceptive methods, particularly during the initial weeks of treatment when gastric emptying effects may be most pronounced

10.3389/fnut.2025.1652598 Front Nutr