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Because of the structural diversity of natural fatty acids, many seemingly homologous enzymes are known for each step of the -oxidation cycle, including auxiliary enzymes for isomerase and reductase reactions together with acyl-CoA thioesterases, which remove any dead-end products

These data functionally validate our KO cell models

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48 Stressors, such as dehydration, fever and infection can lead to a functional decline and neurodegenerative regression in individuals with MD

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Besides its role in energy metabolism, a number of studies have shown that C2 actions range from antioxidant, neuromodulatory, and neuroprotective effects to modulation of gene expression [19,20,21,22]