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Stem Cell Reports 8(1):8494

[Abstract] Expression of synaptophysin in mouse brains in Dihexa-treated (1.44 mg/kg and 2.88 mg/kg) APP/PS1 mice

that is, when pharmacokinetics are linear. In this situation, when the drug is eliminated (ie, metabolized and excreted from the body), the fall in blood level is proportionate to the concentration of the drug in blood