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Duclos-Bastias D

Considering the potential heterogeneity between multiple histological slides within each individual tumor, we set the molecular subtype label for each slide from the overall multiomics subtyping call of the corresponding tumor sample and then performed a random sampling method to identify outliers

The release of neutrophil elastase and matrix metalloproteinases disrupts epithelial barrier integrity, permitting further oxidative insult (134)

Similarly, a study on post-menopausal women (Caucasians and African Americans) found no significant difference in TNF- levels between individuals with or without obesity

While moderate treatment typically results in non-permanent damage 16 , longer treatment times can induce, e.g ., apoptosis 17

The CFs with GSTM1 knockdown exhibited enhanced ECM production even without TGF- stimulation, as indicated by upregulation of fibrotic markers at both mRNA and protein levels compared to the control group (Fig