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CrossRef NADPH Oxidase Inhibition in Fibrotic Pathologies Karen Bernard, Victor J

FTD3 neurons exhibit decreased glycolytic activity and increased mitochondrial TCA turnover It is widely accepted that glucose hypometabolism is a pathological hallmark of several neurodegenerative disorders including FTD [9, 17]

understanding this could guide the development of more selective agents with reduced toxicity

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The aging process of fibroblasts during photoaging owing to UVB exposure is associated with ROS accumulation, which escalates proteasomes inhabitation and autophagy initiation (35)